Official journal of JSPHCS
Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats
Allopurinol is used to treat hyperuricemia and gout. It is metabolized to oxypurinol by xanthine oxidase (XO), and aldehyde oxidase (AO). Allopurinol and oxypurinol are potent XO inhibitors that reduce the pla...