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  1. Gentamicin is a commonly used antibiotic with synergistic effects that is administered once or multiple times daily. However, the influence of the daily administration frequency on renal function has not yet b...

    Authors: Kyohei Sugiyama, Keita Hirai, Yukako Suyama and Masato Tsutsumi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:40
    Content type: Research article Published on:

  2. Treating refractory status epilepticus (RSE) remains a challenge. Thiamylal can be used as a second- or third-line treatment; however, its potential to induce cytochrome P450 (CYP) activity may reduce the conc...

    Authors: Kazutaka Oda, Tomomi Katanoda, Hitomi Arakaki, Taiki Katsume, Kaho Matsuyama, Hirofumi Jono and Hideyuki Saito
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:39
    Content type: Case report Published on:

  3. Perioperative management of patients on dialysis is critical for controlling bleeding and thrombotic risk, in addition to infection control. Postoperative anticoagulation is often difficult to control, and dif...

    Authors: Masanori Suzuki, Yuki Hasegawa, Hiroaki Tanabe, Masayoshi Koinuma and Ryohkan Funakoshi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:38
    Content type: Research article Published on:

  4. Among the oral antivirals used for treating patients with mild-to-moderate novel coronavirus disease 2019 (COVID-19), nirmatrelvir/ritonavir (NMV/RTV) and ensitrelvir (ESV) are inhibitors of cytochrome P450 (C...

    Authors: Hanako Naganawa, Yoshiki Katada, Shunsaku Nakagawa, Keisuke Umemura, Hiroki Ishimura, Moto Kajiwara, Hiroki Endo, Mitsuhiro Sugimoto, Yurie Katsube, Kinuka Kotani, Saki Ohta, Daiki Hira, Masahiro Tsuda, Yuki Kita, Takashi Kobayashi and Tomohiro Terada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:37
    Content type: Case report Published on:

  5. Anamorelin is expected to improve cancer cachexia by increasing lean body mass (LBM) due to increased appetite and protein synthesis. However, the effect of anamorelin on cancer cachexia in real-world practice...

    Authors: Hironori Fujii, Akitaka Makiyama, Kayoko Nishimura, Hirotoshi Iihara, Chiemi Hirose, Koichi Ohata, Yunami Yamada, Daichi Watanabe, Itaru Yasufuku, Naoki Okumura, Yoshihiro Tanaka, Takao Takahashi, Ryo Kobayashi, Nobuhisa Matsuhashi and Akio Suzuki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:36
    Content type: Research article Published on:

  6. We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to qu...

    Authors: Takashi Ohtsuki, Yi Huang, Ayane Kamiya, Yuki Nakayama, Miyuki Matsushita, Satoru Morikawa and Hiroshi Matsufuji
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:35
    Content type: Research article Published on:

  7. Guideline-directed medical therapy (GDMT) is important in heart failure management; however, polypharmacy itself may impact heart failure. Although measures against polypharmacy are needed, current discussion ...

    Authors: Daisuke Hayashi, Yoshiaki Kubota, Takuya Nishino, Yukihiro Watanabe, Yoshiki Iwade, Junya Matsuda, Katsuhito Kato, Shuhei Tara, Yuya Ise, Yu-ki Iwasaki and Kuniya Asai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:34
    Content type: Research article Published on:

  8. Anamorelin, a drug to treat cancer cachexia, binds to ghrelin receptors and improves body weight and appetite. In clinical trials in Japan, patients experienced a 10.7% frequency of stimulant conduction system...

    Authors: Hayato Yokota, Ruriko Asahi, Yumiko Akamine, Mizuki Kobayashi, Hiyu Wakabayashi, Sho Sakamoto, Yuji Okuda, Kazuhiro Sato, Katsutoshi Nakayama and Masafumi Kikuchi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:33
    Content type: Case report Published on:

  9. We aimed to compare anticoagulation control and outcomes between usual medical care (UMC) and pharmacist-led anticoagulation services (PLAS) in patients receiving warfarin at the Tikur Anbessa Specialized Hosp...

    Authors: Tamrat Assefa Tadesse, Amha Gebremedhin, Dejuma Yadeta, Legese Chelkeba and Teferi Gedif Fenta
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:32
    Content type: Research article Published on:

  10. The improvement in flowability and adhesion of starch powder (SP) is essential for using starch as an excipient for lactose intolerant patients. In this study, we attempted to evaluate the usefulness of hydrox...

    Authors: Tomohiro Yoshikawa, Hiroyo Okamoto, Kenta Takeuchi, Atsushi Hirata, Hiroko Otake and Noriaki Nagai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:31
    Content type: Short report Published on:

  11. Based on several case reports and observational studies, there is a growing concern regarding the potential association between roxadustat, a hypoxia-inducible factor prolyl-hydroxylase inhibitor, and suppress...

    Authors: Yuki Nakano, Satoru Mitsuboshi, Kazuhiro Tada and Kosuke Masutani
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:30
    Content type: Research article Published on:

  12. Patient satisfaction is a crucial humanistic outcome metric in pharmacy services. There was a lack of evidence on patients’ satisfaction with pharmacy services in Gamo zone among users and nonusers of the CBHI...

    Authors: Fitsum Teferi Gulta, Tidenek Mulugeta, Biruk Wogayehu and Mende Mensa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:29
    Content type: Research article Published on:

  13. Ganciclovir and its prodrug, valganciclovir, are first-line agents for cytomegalovirus infection prophylaxis after lung transplantation. Although valganciclovir prophylaxis is known to result in severe leukope...

    Authors: Yoshiki Katada, Keisuke Umemura, Shunsaku Nakagawa, Yurie Katsube, Masahiro Tsuda, Satona Tanaka, Hiroshi Date, Miki Nagao and Tomohiro Terada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:28
    Content type: Case report Published on:

  14. People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therapy (ART) for a successful treatment outcome. Understanding the factors associated with i...

    Authors: Yusuke Kunimoto, Shinichi Hikasa, Masashi Ishihara, Mariko Tsukiji, Kazuko Nobori, Takeshi Kimura, Kenta Onishi, Yuuki Yamamoto, Kyohei Haruta, Yohei Kasiwabara, Kenji Fujii and Masahide Fukudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:27
    Content type: Research article Published on:

  15. Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report describes a case where pancreatic metastases disappeared after only two courses of Ipi...

    Authors: Ryo Takada, Miki Fujiwara, Masatoshi Maki, Naoyuki Nomura, Shintaro Kono, Akira Fujita, Hiroshi Masumoto, Yoko Takahashi, Yasuhisa Hasegawa and Koji Tamura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:26
    Content type: Case report Published on:

  16. COMISA is a common disorder that results in nighttime awakenings ,daytime sleepiness and PAP intolerance. Cognitive behavioral therapy for insomnia is used to improve PAP adherence and no medication has been e...

    Authors: Tahereh Madani Motlaq, Besharat Rahimi and Shahideh Amini
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:25
    Content type: Research article Published on:

  17. Pimobendan reportedly improves the subjective symptoms of heart failure. However, evidence of improved prognosis is lacking. This study aimed to determine whether reinforcing guideline-directed medical therapy...

    Authors: Yoshiki Iwade, Yoshiaki Kubota, Daisuke Hayashi, Takuya Nishino, Yukihiro Watanabe, Katsuhito Kato, Shuhei Tara, Yuya Ise and Kuniya Asai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:24
    Content type: Short report Published on:

  18. Coronary heart disease, also known as ischemic heart disease, is induced by atherosclerosis, which is initiated by subendothelial retention of lipoproteins. Plasma lipoproteins, including high density lipoprot...

    Authors: Shin-ya Morita
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:23
    Content type: Review Published on:

  20. Pharmacists should be aware of their thought processes in dispensing work, including differences in the dispensing complexities owing to different drug positions in the left, center, and right areas. Dispensin...

    Authors: Toshikazu Tsuji, Kenichiro Nagata, Masayuki Tanaka, Shigeru Hasebe, Takashi Yukita, Mayako Uchida, Kimitaka Suetsugu, Takeshi Hirota and Ichiro Ieiri
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:21
    Content type: Research article Published on:

  21. The relationship between plasma tenofovir (TFV) concentration at the beginning of tenofovir disoproxil fumarate (TDF) administration and the development of renal dysfunction during long-term administration of ...

    Authors: Hiroki Yagura, Dai Watanabe, Takao Nakauchi, Hiroyuki Kushida, Kazuyuki Hirota, Yasuharu Nishida, Munehiro Yoshino, Tomoko Uehira and Takuma Shirasaka
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:20
    Content type: Research article Published on:

  22. Medication errors related to the pre-admission medication history obtained on admission are a major cause of medication error during hospitalization. Medication reconciliation (MR) improves patient safety thro...

    Authors: Yunami Yamada, Ryo Kobayashi, Taishi Yamamoto, Hironori Fujii, Hirotoshi Iihara, Kato-Hayashi Hiroko, Shohei Nishida, Ryo Hoshino, Takashi Niwa, Keisuke Kumada, Masahito Shimizu and Akio Suzuki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:19
    Content type: Research article Published on:

  23. Patients with a history of hepatitis B virus (HBV) infection who are receiving immunosuppressive therapy are at risk of HBV reactivation and disease. Therefore, HBV screening is required prior to administering...

    Authors: Yuki Yanagisawa, Shungo Imai, Hayato Kizaki and Satoko Hori
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:18
    Content type: Research article Published on:

  24. Methotrexate (MTX) is an antineoplastic/immunosuppressive drug, whose clinical use is impeded owing to its serious adverse effects; one of which is acute kidney injury (AKI). Most of MTX complications emerged ...

    Authors: Mustafa Ahmed Abdel-Reheim, Merhan E. Ali, Ahmed Gaafar A. Gaafar and Ahmed Amine Ashour
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:17
    Content type: Research article Published on:

  25. Human resource management may become complex for community pharmacists owing to recent changes in work volume and content. Few studies have examined job satisfaction, well-being, and quality of work life (QWL)...

    Authors: Yuta Kato, Takashi Sekiya, Ryo Ishii, Yoji Hirako, Hiroki Satoh and Hiromichi Kimura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:16
    Content type: Research article Published on:

  26. Cancer has been identified as a risk factor for severe illness and mortality in coronavirus disease (COVID-19), underscoring the importance of recommending COVID-19 vaccinations to patients with cancer. Howeve...

    Authors: Satoshi Iwakawa, Takuya Azechi, Orie Saigo, Ryunosuke Imai, Ayumi Nakai, Shoji Koshiba, Uki Saito, Kota Asakura, Kuniyoshi Sato and Toshimi Kimura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:15
    Content type: Research article Published on:

  27. Although pharmacists often identify numerous clinical questions, they face several barriers, including the lack of mentors for research activities in clinical settings. Therefore, a workshop for the appropriat...

    Authors: Yuki Asai, Yasushi Takai, Toshiki Murasaka, Tomohiro Miyake, Tomohisa Nakamura, Yoshihiko Morikawa, Yuji Nakagawa, Tatsuya Kanayama, Yasuharu Abe, Naoki Masuda, Yasushi Takamura, Yoshihiro Miki and Takuya Iwamoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:14
    Content type: Short report Published on:

  28. Continued use of tenofovir disoproxil fumarate (TDF), an antiretroviral drug, causes renal function decline and tubular damage in individuals with HIV. While tenofovir alafenamide fumarate (TAF) may have less ...

    Authors: Kensuke Abe, Junji Imamura, Akiko Sasaki, Tomoko Suzuki, Satomi Kamio, Taku Obara and Toshihiro Ito
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:13
    Content type: Research article Published on:

  29. Infusion-related reactions (IRRs) are major side effects of rituximab administration. Male sex, high body weight, body surface area (BSA), and body mass index are predictive markers of rituximab-induced IRRs. ...

    Authors: Hironobu Nishiura, Masaya Takahashi, Katsuhito Mori, Takashi Sugimoto, Masanori Emoto and Yasutaka Nakamura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:12
    Content type: Short report Published on:

  30. We evaluated the predictive factors for surgical site infections (SSIs) in elective colorectal cancer surgery and the role of antimicrobial stewardship (AS) pharmacists in modifying the clinical pathway.

    Authors: Yasuhiro Sasaki, Akira Kurishima, Chieko Miyamoto, Kenichiro Hataji, Toru Tezuka and Hideo Katsuragawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:11
    Content type: Short report Published on:

  31. Pembrolizumab can cause immune-related adverse events such as adrenal insufficiency (AI). However, there is no consensus regarding appropriate monitoring of adrenal function during subsequent chemotherapy in p...

    Authors: Tatsuhiro Fujimiya, Kanako Azuma, Yuki Togashi, Koji Kuwata, Sakae Unezaki and Hironori Takeuchi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:10
    Content type: Case report Published on:

  32. Hospital pharmacists are important in antibiotic stewardship programs (ASP), a global strategy to combat antibiotic resistance (ABR). South African public hospitals have limited ASP implementation. This study ...

    Authors: Tiyani Comfort Mthombeni, Johanita Riétte Burger, Martha Susanna Lubbe and Marlene Julyan
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:9
    Content type: Research article Published on:

  33. Corticosteroid-containing medications are widely accessible in various forms, including topical, injectable, and inhaled formulations. Due to uncertain safety profiles, healthcare providers, including pharmaci...

    Authors: Muna Barakat, Samar Thiab, Rana Abu Farha, Anas O. Alshweiki, Roa’a Thaher, Asem Alsughaier and Diana Malaeb
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:8
    Content type: Research article Published on:

  34. Multidrug-resistant bacterial strains cause several serious infections that can be fatal, such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumonia, Acinetobacter baumannii, Pseudomonas aeruginosa

    Authors: Showkat Ahmad Bhat, Mohammed Iqbal Zargar, Shahid Ud Din Wani, Ishfaq Mohiuddin, Mubashir Hussain Masoodi, Faiyaz Shakeel, Mohammad Ali and Seema Mehdi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:7
    Content type: Research article Published on:

  35. Hospitals in Japan established the healthcare delivery system from FY 2018 to 2021 by acquiring an additional reimbursement for infection prevention (ARIP) of category 1 or 2. However, research on outcomes of ...

    Authors: Yuichi Tasaka, Takeshi Uchikura, Shiro Hatakeyama, Daisuke Kikuchi, Masami Tsuchiya, Ryohkan Funakoshi and Taku Obara
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:6
    Content type: Research article Published on:

  36. Therapeutic drug monitoring (TDM) systems generally use either liquid chromatography/tandem mass spectrometry (LC-MS/MS) or immunoassay, though both methodologies have disadvantages. In this study, we aimed to...

    Authors: Tsutomu Shimada, Daisuke Kawakami, Arimi Fujita, Rintaro Yamamoto, Satoshi Hara, Kiyoaki Ito, Ichiro Mizushima, Shinji Kitajima, Yasunori Iwata, Norihiko Sakai, Mitsuhiro Kawano, Takashi Wada and Yoshimichi Sai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:5
    Content type: Research article Published on:

  37. As methadone can prevent the development of opioid resistance, it has application in alleviating cancer-related pain that proves challenging to manage with other opioids. QT interval prolongation is a serious ...

    Authors: Ryusuke Ouchi, Munenori Nagao, Shinju Suzuki, Toshihiro Yamagata, Mie Chiba, Naoko Kurata, Kensuke Usui, Takashi Watanabe, Kaori Koyama and Kouji Okada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:4
    Content type: Case report Published on:

  38. Hemophilia is a rare genetic condition that is often overlooked and underdiagnosed, particularly in low-income countries. Long-term spontaneous joint bleeding and soft tissues can have a significant negative i...

    Authors: Sitina Iyar, Girma Tekle Gebremariam, Dessale Abate Beyene, Amha Gebremedhin and Tamrat Assefa Tadesse
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:3
    Content type: Research article Published on:

  39. Schizophrenia is a psychiatric disorder characterized by hallucinations, delusions, and other symptoms. Although treatment guidelines for schizophrenia have been established in Japan, drugs are not recommended...

    Authors: Daisuke Kikuchi, Taku Obara, Ryo Obara, Hiroaki Hino, Naoto Suzuki, Shota Kashiwagura, Takashi Watanabe, Ryusuke Ouchi, Kensuke Usui and Kouji Okada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:2
    Content type: Short report Published on:

  40. Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It has a wide range of clinical applications in various cancers and retinal diseases. The drugs entered the Chinese market by a ...

    Authors: Li Wang, Yibo Fei, Han Qu, Haiyang Zhang, Yuanyuan Wang, Zhenghua Wu and Guorong Fan
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:1
    Content type: Research article Published on:

  41. Pharmaceutical companies do not sell formulations for all diseases; thus, healthcare workers have to treat some diseases by concocting in-hospital preparations. An example is the high-concentration 2% cyclospo...

    Authors: Masakazu Ozaki, Toshihiko Kobayashi, Aki Fujinaga, Mitsuaki Nishioka, Kyoko Shikichi, Satoshi Okano, Yasuhito Sakai, Sayumi Fujii, Nobuaki Matsui, Miwako Takasago, Naoto Okada, Takahiro Yamasaki and Takashi Kitahara
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:50
    Content type: Research article Published on:

  42. Nucleoside analogues (NAs) such as entecavir are required for at least 12 months when patients with resolved hepatitis B virus (HBV) infection develop HBV reactivation. Entecavir treatment does not always achi...

    Authors: Maki Ohkubo, Kuniaki Fukuda, Shigeru Chiba and Masato Homma
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:52
    Content type: Case report Published on:

  43. We developed a bleeding risk scoring system (BRSS) using prophylactic anticoagulation therapy to comprehensively assess the risk of venous thromboembolism (VTE) in trauma patients. This study evaluated the use...

    Authors: Atsushi Tomizawa, Takaaki Maruhashi, Akito Shibuya, Akihiko Akamine, Masayuki Kuroiwa, Yuichi Kataoka, Yasushi Asari, Koichiro Atsuda and Katsuya Otori
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:48
    Content type: Research article Published on:

  44. Bleeding risk factors in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) are unclear and data on the use of antithrombotic drugs are lacking. We investigated the b...

    Authors: Kanako Fujita, Noriko Kohyama, Miki Sato, Tomokazu Deguchi, Hiroshi Suzuki, Mio Ebato and Mari Kogo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:41
    Content type: Research article Published on:

  45. A reduction in the brain-derived neurotrophic factor (BDNF) level in the brain causes depression, whereas an increase in its level has therapeutic benefits against depression. BDNF is synthesized in various pe...

    Authors: Kensuke Nakajima, Shinya Okubo, Tomoe Ohta, Takuhiro Uto and Shigeru Oiso
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:40
    Content type: Research article Published on:

  46. Prescribing with high levels of medical appropriateness and patient satisfaction improves adherence. However, its appropriateness does not always match patient preference. Deprescription is important for ensur...

    Authors: Sayaka Arai, Takahiro Ishikawa, Kenichi Arai, Takaaki Suzuki and Itsuko Ishii
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:51
    Content type: Research article Published on:

  47. Our case is the first report showing the development of hypoglycemia following the administration of vadadustat in a patient with chronic kidney disease being treated with mitiglinide and sitagliptin, possibly...

    Authors: Ayumi Takakura, Toshinori Hirai, Naomi Hamaguchi, Rika Mukohara, Kazutaka Matsumoto, Yutaka Yano and Takuya Iwamoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:46
    Content type: Case report Published on:

  48. In most countries barring Japan, antihypertensive drug use has been reported using the defined daily doses/1000 inhabitants/day (DID). Although DID has been shown to allow for the assessment of the number of p...

    Authors: Kanako Mizuno, Ryo Inose, Yukina Yoshimura and Yuichi Muraki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:47
    Content type: Research article Published on:

  49. Long-term care issues, specifically metabolic bone disorders, are a concern for people living with human immunodeficiency virus (PLWH) who undergo life-long antiretroviral therapy (ART). Previous clinical tria...

    Authors: Yusuke Kunimoto, Ryosuke Matamura, Hiroshi Ikeda, Hiroto Horiguchi, Satoshi Fujii, Masayoshi Kobune, Masahide Fukudo and Takaki Toda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:45
    Content type: Research article Published on:

  50. Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration ...

    Authors: Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki and Tappei Takada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:38
    Content type: Research article Published on:
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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