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  1. Crizotinib, an ATP-competitive receptor tyrosine kinase inhibitor of both anaplastic lymphoma kinase (ALK) and the hepatocyte growth factor receptor, commonly causes several adverse events (AEs). The clinical ...

    Authors: Yasuko Kurata, Narumi Miyauchi, Manabu Suno, Takahiro Ito, Toshiaki Sendo and Katsuyuki Kiura

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:8

    Content type: Short report

    Published on:

  2. It is well known that molecular-targeted drugs, of which sorafenib (Nexavar®) is one, differ from previous anticancer drugs and cause various unusual adverse drug reactions. Treatment with sorafenib causes adv...

    Authors: Makoto Kajizono, Megumu Aoyagi, Yoshihisa Kitamura and Toshiaki Sendo

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:6

    Content type: Research article

    Published on:

  3. The lower urinary tract symptoms (LUTS) increases with age and can have a significant effect on the quality of life of the patients. Elderly patients, who are often characterized by a decline in physiological ...

    Authors: Masako Hashimoto, Kanako Hashimoto, Fumihiko Ando, Yoshiaki Kimura, Keisuke Nagase and Kunizo Arai

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:7

    Content type: Research article

    Published on:

  4. Tramadol ((±)-TRA) is recommended for the treatment of mild to moderate cancer pain by the World Health Organization. An oral liquid formulation of (±)-TRA is preferable for patients with a compromised swallow...

    Authors: Manabu Suno, Hidenori Ichihara, Takahiro Ishino, Kento Yamamoto and Yuta Yoshizaki

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:5

    Content type: Research article

    Published on:

  5. Delirium is an acute change in cognition and concentration that complicates the postoperative course. Patients who suffer delirium after surgery have an increased risk of persistent cognitive impairment, funct...

    Authors: Kiminaka Murakawa, Yoshihisa Kitamura, Saori Watanabe, Shiho Hongo, Kazuaki Shinomiya and Toshiaki Sendo

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:4

    Content type: Research article

    Published on:

  6. In the construction of pharmacoeoconomic models, simplicity is desirable for transparency (people can see how the model is built), ease of analysis, validation (how well the model reproduces reality), and desc...

    Authors: Takeshi Uchikura, Makoto Kobayashi, Masayuki Hashiguchi and Mayumi Mochizuki

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:3

    Content type: Research article

    Published on:

  7. To improve the adherence to and knowledge about pharmacotherapy in outpatients and to maximize the efficacy and minimize the adverse drug events, the first pharmacist-managed clinic (PMC) in Japan was establis...

    Authors: Kiyofumi Yamada and Toshitaka Nabeshima

    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:2

    Content type: Review

    Published on:

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