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  1. Research article

    Association between itching and the serum zinc levels in patients with varicose veins

    Varicose veins commonly occur in the lower extremities and can cause pain and discomfort in the affected area. Many patients with varicose veins suffer from itching, but its cause has not been sufficiently exp...

    Yasushi Takai, Keiichi Hiramoto, Yoshiyuki Nishimura, Ryota Uchida, Keigo Nishida and Kazuya Ooi

    Journal of Pharmaceutical Health Care and Sciences 2017 3:24

    Published on: 21 September 2017

  2. Case report

    Efficacy of switching to dolutegravir plus rilpivirine, the small-tablet regimen, in patients with dysphagia: two case reports

    The advent of well-tolerated and effective anti-retroviral drugs against human immunodeficiency virus-1 (HIV-1) infection has been a major step forward that has achieved long-term survival in recent years. The...

    Takefumi Suzuki, Nobuko Hara, Morichika Osa, Kazuhisa Misawa, Kazuo Imai, Yuji Fujikura, Takuya Maeda, Wataru Sonehara and Akihiko Kawana

    Journal of Pharmaceutical Health Care and Sciences 2017 3:23

    Published on: 19 September 2017

  3. Research article

    The detection of influenza virus at the community pharmacy to improve the management of local residents with influenza or influenza-like disease

    As of 2014, community pharmacies in Japan are approved by the Ministry of Health, Labour and Welfare to measure lipid panel, HbA1c, glucose, ALT, AST and γ-GTP, but not to screen for influenza virus. We provid...

    Akio Kawachi, Yusuke Sakamoto, Shunya Mouri, Mitsuaki Fukumori, Riku Kawano, Takaya Murakami, Junichiro Sonoda, Keiko Narumi, Yoshihiro Shimodozono, Kenji Etoh, Susumu Chiyotanda, Takashi Furuie, Keizo Sato, Masao Fukumori and Toshiro Motoya

    Journal of Pharmaceutical Health Care and Sciences 2017 3:22

    Published on: 8 August 2017

  4. Research article

    Objective evaluation of chemotherapy-induced peripheral neuropathy using quantitative pain measurement system (Pain Vision®), a pilot study

    In an evaluation of chemotherapy-induced peripheral neuropathy (CIPN), objectivity may be poor because the evaluation is determined by the patient’s subjective assessment. In such cases, management of neuropat...

    Junya Sato, Megumi Mori, Satoru Nihei, Satoshi Takeuchi, Masahiro Kashiwaba and Kenzo Kudo

    Journal of Pharmaceutical Health Care and Sciences 2017 3:21

    Published on: 25 July 2017

  5. Research article

    Kamishoyosan and Shakuyakukanzoto promote recovery from paclitaxel-induced neurite retraction in PC12 cells

    In chemotherapy, the full round of treatment must be completed as scheduled to achieve the strongest therapeutic effect. However, peripheral neuropathy, a severe side effect of the chemotherapeutic agent pacli...

    Ken Konaka, Kota Moriyama, Takumi Sakurada, Naoto Okada, Masaki Imanishi, Yoshito Zamami, Kazuyoshi Kawazoe, Shuji Fushitani and Keisuke Ishizawa

    Journal of Pharmaceutical Health Care and Sciences 2017 3:20

    Published on: 21 July 2017

  6. Research article

    Drug-induced gingival hyperplasia: a retrospective study using spontaneous reporting system databases

    Drug-induced gingival hyperplasia (DIGH) causes problems with chewing, aesthetics, and pronunciation, and leads to the deterioration of the patient’s quality of life (QOL). Thus, the aim of this study was to e...

    Haruna Hatahira, Junko Abe, Yuuki Hane, Toshinobu Matsui, Sayaka Sasaoka, Yumi Motooka, Shiori Hasegawa, Akiho Fukuda, Misa Naganuma, Tomofumi Ohmori, Yasutomi Kinosada and Mitsuhiro Nakamura

    Journal of Pharmaceutical Health Care and Sciences 2017 3:19

    Published on: 19 July 2017

  7. Research article

    Usefulness of limited sampling strategy for mycophenolic acid area under the curve considering postoperative days in living-donor renal transplant recipients with concomitant prolonged-release tacrolimus

    The optimal dose of mycophenolate mofetil (MMF) in renal transplant patients has been recommended to be decided on the basis of area under the concentration-time curve (AUC0-12) of mycophenolic acid (MPA). Althou...

    Tomoyuki Enokiya, Kouhei Nishikawa, Yuichi Muraki, Takuya Iwamoto, Hideki Kanda, Yoshiki Sugimura and Masahiro Okuda

    Journal of Pharmaceutical Health Care and Sciences 2017 3:17

    Published on: 24 June 2017

  8. Research article

    Development and evaluation of adsorption sheet (HD safe sheet-U) using active carbon for the purpose of the preventing the contamination diffusion of urinary excreted anticancer drug

    Certain amount of anticancer drugs is excreted in the urine of patients receiving anticancer drugs, and urinary scattering including anticancer drugs at excretion has become a route of anticancer drug contamin...

    Junya Sato, Haruka Ohkubo, Yuki Sasaki, Makoto Yokoi, Yasunori Hotta and Kenzo Kudo

    Journal of Pharmaceutical Health Care and Sciences 2017 3:16

    Published on: 2 June 2017

  9. Research article

    Effects of resistant dextrin for weight loss in overweight adults: a systematic review with a meta-analysis of randomized controlled trials

    Randomized controlled trials (RCTs) reported that resistant dextrin (RD) exerted pleiotropic effects on humans. However, limited information is available on the effects of RD for weight loss. We conducted a sy...

    Junichi Mukai, Yuta Tsuge, Michiko Yamada, Katsuya Otori and Koichiro Atsuda

    Journal of Pharmaceutical Health Care and Sciences 2017 3:15

    Published on: 16 May 2017

  10. Research article

    Effect of health foods on cytochrome P450-mediated drug metabolism

    Health foods have been widely sold and consumed in Japan. There has been an increase in reports of adverse effects in association with the expanding health food market. While health food-drug interactions are ...

    Takamitsu Sasaki, Yu Sato, Takeshi Kumagai, Kouichi Yoshinari and Kiyoshi Nagata

    Journal of Pharmaceutical Health Care and Sciences 2017 3:14

    Published on: 10 May 2017

  11. Research article

    Evaluation of the permeation of antineoplastic agents through medical gloves of varying materials and thickness and with varying surface treatments

    Medical gloves are an important piece of personal protective equipment that prevents exposure to antineoplastic agents. The permeability of medical gloves to antineoplastic agents is a crucial factor in the ap...

    Toyohito Oriyama, Takehito Yamamoto, Yoshitsugu Yanagihara, Katsuhiko Nara, Toshihide Abe, Katsuyoshi Nakajima, Takao Aoyama and Hiroshi Suzuki

    Journal of Pharmaceutical Health Care and Sciences 2017 3:13

    Published on: 2 May 2017

  12. Research article

    Effects of communication skill training (CST) based on SPIKES for insurance-covered pharmacy pharmacists to interact with simulated cancer patients

    With the development of pharmacotherapy and radiotherapy, cancer treatment is being shifted from surgical to outpatient services, consequently increasing insurance-covered pharmacies’ frequency of dealing with...

    Manako Hanya, Yoshitake Kanno, Junko Akasaki, Keiko Abe, Kazuhiko Fujisaki and Hiroyuki Kamei

    Journal of Pharmaceutical Health Care and Sciences 2017 3:11

    Published on: 8 April 2017

  13. Research article

    Influence of nonsteroidal anti-inflammatory drugs on aspirin’s antiplatelet effects and suggestion of the most suitable time for administration of both agents without resulting in interaction

    Low-dose aspirin irreversibly inhibits platelet cyclooxygenase-1 (COX-1) and suppresses platelet aggregation. It is effective for secondary prevention of cardiovascular events. Because nonsteroidal anti-inflam...

    Kenta Shibata, Yuuki Akagi, Naofumi Nozawa, Hitoshi Shimomura and Takao Aoyama

    Journal of Pharmaceutical Health Care and Sciences 2017 3:9

    Published on: 9 March 2017

    The Erratum to this article has been published in Journal of Pharmaceutical Health Care and Sciences 2017 3:10

  14. Research article

    Comparison of 16S ribosomal RNA gene sequence analysis and conventional culture in the environmental survey of a hospital

    Nosocomial infection is one of the most common complications within health care facilities. Certain studies have reported outbreaks resulting from contaminated hospital environments. Although the identificatio...

    Akihiro Manaka, Yutaka Tokue and Masami Murakami

    Journal of Pharmaceutical Health Care and Sciences 2017 3:8

    Published on: 19 January 2017

  15. Research article

    Drug interaction between methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritis

    Methotrexate (MTX) and salazosulfapyridine (SASP) are disease-modifying drugs that are commonly used in the treatment of rheumatoid arthritis (RA), and combination therapy with MTX and SASP is recommended for ...

    Morihiro Okada, Hiroshi Fujii, Yukio Suga, Satoshi Morito, Masae Okada, Jun Nishigami, Mitsuhiro Kawano, Tsutomu Shimada and Yoshimichi Sai

    Journal of Pharmaceutical Health Care and Sciences 2017 3:7

    Published on: 19 January 2017

  16. Research article

    Predictive factors for effectiveness and safety of enoxaparin for total knee arthroplasty in aged Japanese patients: a retrospective review

    The aims of this study were to investigate predictive factors involved in effectiveness and safety of enoxaparin for prevention of postoperative venous thromboembolism in aged Japanese total knee arthroplasty ...

    Akihiro Sonoda, Yuki Kondo, Yasuhiro Tsuneyoshi, Yoshitaka Iwashita, Shoji Nakao, Kazuhisa Ishida, Kentaro Oniki, Junji Saruwatari, Tetsumi Irie and Yoichi Ishitsuka

    Journal of Pharmaceutical Health Care and Sciences 2017 3:6

    Published on: 18 January 2017

  17. Research article

    Appropriate use of a dry powder inhaler based on inhalation flow pattern

    An optimal inhalation flow pattern is essential for effective use of a dry powder inhaler (DPI). We wondered whether DPI instructors inhale from a DPI with an appropriate pattern, and if not, whether self-trai...

    Tetsuri Kondo, Makoto Hibino, Toshimori Tanigaki, Stanley M. Cassan, Sakurako Tajiri and Kenichro Akazawa

    Journal of Pharmaceutical Health Care and Sciences 2017 3:5

    Published on: 18 January 2017

  18. Research article

    Impact of Pharmacists’ audit on improving the quality of prescription of dabigatran etexilate methanesulfonate: a retrospective study

    Appropriate prescription of dabigatran etexilate methanesulfonate (JAN) is more complicated than assumed, because there are totally 10 items of contraindications and instructions for dosage reduction depending...

    Teppei Shimizu, Yoshio Momose, Ryuichi Ogawa, Masahiro Takahashi and Hirotoshi Echizen

    Journal of Pharmaceutical Health Care and Sciences 2017 3:4

    Published on: 17 January 2017

  19. Research article

    Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastine, adriamycin and cisplatin chemotherapy: a retrospective cohort study

    Bladder cancer patients receiving methotrexate, vinblastine, adriamycin and cisplatin (MVAC) chemotherapy are co-administered with dexamethasone as an anti-emetic. We examined whether or not dexamethasone affe...

    Shingo Itai, Yukio Suga, Yusuke Hara, Kouji Izumi, Yuji Maeda, Yasuhide Kitagawa, Junko Ishizaki, Tsutomu Shimada, Atsushi Mizokami and Yoshimichi Sai

    Journal of Pharmaceutical Health Care and Sciences 2017 3:3

    Published on: 11 January 2017

  20. Research article

    Development and evaluation of a formula for predicting introduction of medication self-management in stroke patients in the Kaifukuki rehabilitation ward

    Medication self-management in stroke patients is important to prevent further progression of disease and incidence of side effects. The purpose of this study was to create a formula for predicting medication s...

    Hisato Fujihara, Mari Kogo, Isao Saito, Nobuyuki Kawate, Masazumi Mizuma, Hiroko Suzuki, Jun-ichiro Murayama and Tadanori Sasaki

    Journal of Pharmaceutical Health Care and Sciences 2017 3:2

    Published on: 10 January 2017

  21. Research article

    Optimal dosage of cefmetazole for intraoperative antimicrobial prophylaxis in patients undergoing surgery for colorectal cancer

    Few studies have reported the dosage of cefmetazole (CMZ) for intraoperative antimicrobial prophylaxis in patients underwent surgery for colorectal cancer. We therefore examined the optimal intraoperative dosa...

    Atsushi Tomizawa, Takatoshi Nakamura, Toshiaki Komatsu, Hiroshi Inano, Rumiko Kondo, Masahiko Watanabe and Koichiro Atsuda

    Journal of Pharmaceutical Health Care and Sciences 2017 3:1

    Published on: 7 January 2017

  22. Research article

    Genetic polymorphisms of enzyme proteins and transporters related to methotrexate response and pharmacokinetics in a Japanese population

    Methotrexate (MTX) is currently the anchor drug widely used worldwide in the treatment of rheumatoid arthritis (RA). However, the therapeutic response to MTX has been shown to vary widely among individuals, ge...

    Masayuki Hashiguchi, Mikiko Shimizu, Jun Hakamata, Tomomi Tsuru, Takanori Tanaka, Midori Suzaki, Kumika Miyawaki, Takeshi Chiyoda, Osamu Takeuchi, Jiro Hiratsuka, Shin Irie, Junya Maruyama and Mayumi Mochizuki

    Journal of Pharmaceutical Health Care and Sciences 2016 2:35

    Published on: 9 December 2016

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